prikaz prve stranice dokumenta Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro
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Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro
Plants, 11 (2022), 3; 271. https://doi.org/10.3390/plants11030271
Šola, Ivana; Poljuha, Danijela; Mikulic- Petkovsek, Maja; Davosir, Dino; Pinterić, Marija; Bilić, Josipa; Veberic, Robert; Hudina, Metka; Rusak, Gordana

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Šola, I., Poljuha, D., Mikulic Petkovsek, M., Davosir, D., Pinterić, M., Bilić, J. ... Rusak, G. (2022). Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro. Plants, 11. (3). doi: 10.3390/plants11030271

Šola, Ivana, et al. "Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro." Plants, vol. 11, br. 3, 2022. https://doi.org/10.3390/plants11030271

Šola, Ivana, Danijela Poljuha, Maja Mikulic Petkovsek, Dino Davosir, Marija Pinterić, Josipa Bilić, Robert Veberic, Metka Hudina i Gordana Rusak. "Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro." Plants 11, br. 3 (2022). https://doi.org/10.3390/plants11030271

Šola, I., et al. (2022) 'Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro', Plants, 11(3). doi: 10.3390/plants11030271

Šola I, Poljuha D, Mikulic Petkovsek M, Davosir D, Pinterić M, Bilić J, i sur.. Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro. Plants [Internet]. 2022. [pristupljeno 23.02.2025.];11(3). doi: 10.3390/plants11030271

I. Šola, et al., "Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro", Plants, vol. 11, br. 3, 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:212:214984. [Citirano: 23.02.2025.]

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Naslov (engleski)Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro
AutorIvana Šola
AutorDanijela Poljuha
AutorMaja Mikulic- Petkovsek
AutorDino Davosir
AutorMarija Pinterić
AutorJosipa Bilić
AutorRobert Veberic
AutorMetka Hudina
AutorGordana Rusak
Autorova ustanovaIstarsko veleučilište - Universita Istriana di scienze applicate
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Biologija
Sažetak (engleski)
The aim of this work was to assess the biopotential of the young inflorescence tissues of Prunus, Malus and Chaenomeles in order to evaluate the possibility of their application in the food industry, and to provide a polyphenolic fingerprint for their quality control. The contents of different bioactive compounds and their antioxidant capacities were spectrophotometrically measured, the main phenolic compounds were identified and quantified using LC- DAD-MS, the antidiabetic potential was determined using α-amylase and α-glucosidase inhibition assays, the anti-inflammatory potential was determined using a 5-lipoxygenase inhibition assay, and the cytotoxicity was determined by MTT assay. Using one- way ANOVA, principal component analysis, hierarchical clustering and Pearson’s correlation coefficient, the relations between the samples, and between the samples and the measured parameters, were revealed. In total, 77 compounds were identified. The concentration of sugars was low in M. purpurea, at 1.56 ± 0.08 mg/g DW. The most effective sample in the inhibition of antidiabetic enzymes and anti- inflammatory 5- lipoxygenase was C. japonica. The inhibition of α- glucosidase was strongly positively correlated with the total and condensed tannins, procyanidin dimers and procyanidin tetramer, and was very strongly correlated with chlorogenic acid. In α- amylase inhibition, C. japonica and P. serrulata ‘Kiku Shidare Zakura’ were equally efficient to the standard inhibitor, maltose. The most effective in the growth and proliferation inhibition of HepG2, HCT116 and HaCaT cells was P. avium. The results suggest Prunus, Malus and Chaenomeles inflorescences as functional food ingredients.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPlants
Brojčani podacivol. 11, br. 3, 271
e-ISSN2223-7747
DOIhttps://doi.org/10.3390/plants11030271
URN:NBNurn:nbn:hr:212:214984
Datum objave publikacije2022
URL dokumentahttps://www.mdpi.com/2223-7747/11/3/271
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-02-18 12:05:25