prikaz prve stranice dokumenta Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro
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Scientific paper - Original scientific paper
Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro
Plants, 11 (2022), 3; 271. https://doi.org/10.3390/plants11030271
Šola, Ivana; Poljuha, Danijela; Mikulic- Petkovsek, Maja; Davosir, Dino; Pinterić, Marija; Bilić, Josipa; Veberic, Robert; Hudina, Metka; Rusak, Gordana

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Šola, I., Poljuha, D., Mikulic Petkovsek, M., Davosir, D., Pinterić, M., Bilić, J. ... Rusak, G. (2022). Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro. Plants, 11. (3). doi: 10.3390/plants11030271

Šola, Ivana, et al. "Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro." Plants, vol. 11, no. 3, 2022. https://doi.org/10.3390/plants11030271

Šola, Ivana, Danijela Poljuha, Maja Mikulic Petkovsek, Dino Davosir, Marija Pinterić, Josipa Bilić, Robert Veberic, Metka Hudina and Gordana Rusak. "Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro." Plants 11, no. 3 (2022). https://doi.org/10.3390/plants11030271

Šola, I., et al. (2022) 'Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro', Plants, 11(3). doi: 10.3390/plants11030271

Šola I, Poljuha D, Mikulic Petkovsek M, Davosir D, Pinterić M, Bilić J, and sur.. Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro. Plants [Internet]. 2022 [cited 2025 February 23];11(3). doi: 10.3390/plants11030271

I. Šola, et al., "Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro", Plants, vol. 11, no. 3, 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:212:214984. [Accessed: 23 February 2025]

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Metadata
Title (english)Biopotential of Underutilized Rosaceae Inflorescences: LC-DAD-MS Phytochemical Profiles Associated with Antioxidant, Antidiabetic, Anti- Inflammatory and Antiproliferative Activity In Vitro
AuthorIvana Šola
AuthorDanijela Poljuha
AuthorMaja Mikulic- Petkovsek
AuthorDino Davosir
AuthorMarija Pinterić
AuthorJosipa Bilić
AuthorRobert Veberic
AuthorMetka Hudina
AuthorGordana Rusak
Author's institutionIstrian University of applied sciences
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract (english)
The aim of this work was to assess the biopotential of the young inflorescence tissues of Prunus, Malus and Chaenomeles in order to evaluate the possibility of their application in the food industry, and to provide a polyphenolic fingerprint for their quality control. The contents of different bioactive compounds and their antioxidant capacities were spectrophotometrically measured, the main phenolic compounds were identified and quantified using LC- DAD-MS, the antidiabetic potential was determined using α-amylase and α-glucosidase inhibition assays, the anti-inflammatory potential was determined using a 5-lipoxygenase inhibition assay, and the cytotoxicity was determined by MTT assay. Using one- way ANOVA, principal component analysis, hierarchical clustering and Pearson’s correlation coefficient, the relations between the samples, and between the samples and the measured parameters, were revealed. In total, 77 compounds were identified. The concentration of sugars was low in M. purpurea, at 1.56 ± 0.08 mg/g DW. The most effective sample in the inhibition of antidiabetic enzymes and anti- inflammatory 5- lipoxygenase was C. japonica. The inhibition of α- glucosidase was strongly positively correlated with the total and condensed tannins, procyanidin dimers and procyanidin tetramer, and was very strongly correlated with chlorogenic acid. In α- amylase inhibition, C. japonica and P. serrulata ‘Kiku Shidare Zakura’ were equally efficient to the standard inhibitor, maltose. The most effective in the growth and proliferation inhibition of HepG2, HCT116 and HaCaT cells was P. avium. The results suggest Prunus, Malus and Chaenomeles inflorescences as functional food ingredients.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titlePlants
Numberingvol. 11, no. 3, 271
e-ISSN2223-7747
DOIhttps://doi.org/10.3390/plants11030271
URN:NBNurn:nbn:hr:212:214984
Publication2022
Document URLhttps://www.mdpi.com/2223-7747/11/3/271
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2025-02-18 12:05:25